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Wolfgang Hiddemann Selected Research

Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)

12/2022SAKK 35/15: a phase 1 trial of obinutuzumab in combination with venetoclax in patients with previously untreated follicular lymphoma.
3/2022Immunochemotherapy and Maintenance With Obinutuzumab or Rituximab in Patients With Previously Untreated Marginal Zone Lymphoma in the Randomized GALLIUM Trial.
1/2022Genomic and microenvironmental landscape of stage I follicular lymphoma, compared with stage III/IV.
10/2021Single-nucleotide Fcγ receptor polymorphisms do not impact obinutuzumab/rituximab outcome in patients with lymphoma.
7/2021Rituximab Maintenance Versus Observation After Immunochemotherapy (R-CHOP, R-MCP, and R-FCM) in Untreated Follicular Lymphoma Patients: A Randomized Trial of the Ostdeutsche Studiengruppe Hämatologie und Onkologie and the German Low-Grade Lymphoma Study Group.
12/2020Venetoclax-rituximab with or without bendamustine vs bendamustine-rituximab in relapsed/refractory follicular lymphoma.
12/2020Follicular Lymphoma Evaluation Index (FLEX): A new clinical prognostic model that is superior to existing risk scores for predicting progression-free survival and early treatment failure after frontline immunochemotherapy.
5/2020Association of early disease progression and very poor survival in the GALLIUM study in follicular lymphoma: benefit of obinutuzumab in reducing the rate of early progression.
1/2020Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma.
1/2020Impact of bone marrow biopsy on response assessment in immunochemotherapy-treated lymphoma patients in GALLIUM and GOYA.
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Wolfgang Hiddemann Research Topics

Disease

74Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
06/2022 - 07/2002
42Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
12/2022 - 01/2003
36Neoplasms (Cancer)
09/2022 - 07/2002
24Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
09/2021 - 01/2003
23Leukemia
09/2022 - 09/2002
20Lymphoma (Lymphomas)
03/2022 - 01/2003
16Non-Hodgkin Lymphoma (Lymphosarcoma)
07/2021 - 01/2003
7Disease Progression
05/2020 - 06/2003
7B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2018 - 06/2002
6Acute Promyelocytic Leukemia
12/2021 - 01/2002
6Hematologic Neoplasms (Hematological Malignancy)
10/2020 - 12/2004
5Sarcoma (Soft Tissue Sarcoma)
04/2018 - 07/2002
4Infections
10/2018 - 09/2002
4Hyperthermia
04/2018 - 07/2002
4Residual Neoplasm
01/2018 - 03/2006
4Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/2016 - 08/2003
4Myelodysplastic Syndromes (Myelodysplastic Syndrome)
04/2009 - 12/2004
3Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
10/2021 - 01/2019
3Myeloid Leukemia (Leukemia, Myelocytic)
01/2020 - 01/2003
3Pathologic Complete Response
01/2018 - 11/2004
2Death (Near-Death Experience)
01/2017 - 11/2012
2Systemic Inflammatory Response Syndrome (Sepsis Syndrome)
01/2016 - 05/2006
2Graft vs Host Disease (Graft-Versus-Host Disease)
10/2012 - 01/2005
2Trisomy (Trisomies)
07/2011 - 09/2002
2Genetic Translocation (Chromosomal Translocation)
12/2009 - 01/2009
2Neutropenia
04/2009 - 09/2003
2Chromosome Aberrations (Chromosome Abnormalities)
04/2007 - 09/2002
1Thrombocytopenia (Thrombopenia)
12/2022

Drug/Important Bio-Agent (IBA)

32Rituximab (Mabthera)FDA Link
03/2022 - 01/2003
17Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2019 - 01/2003
14Doxorubicin (Adriamycin)FDA LinkGeneric
01/2019 - 09/2003
13obinutuzumabIBA
12/2022 - 02/2015
12Monoclonal AntibodiesIBA
01/2020 - 04/2003
11Cytarabine (Cytosar-U)FDA LinkGeneric
09/2021 - 12/2003
11Vincristine (Oncovin)FDA LinkGeneric
01/2019 - 09/2003
10Prednisone (Sone)FDA LinkGeneric
01/2019 - 12/2004
9GalliumIBA
03/2022 - 10/2018
9Proteins (Proteins, Gene)FDA Link
08/2013 - 08/2002
8Mitoxantrone (Novantrone)FDA LinkGeneric
12/2018 - 01/2003
8AntibodiesIBA
02/2015 - 06/2003
7Biomarkers (Surrogate Marker)IBA
09/2022 - 08/2007
6DNA (Deoxyribonucleic Acid)IBA
01/2019 - 07/2003
6fludarabineIBA
01/2018 - 06/2002
6Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2014 - 02/2003
5Biological ProductsIBA
01/2022 - 10/2003
5Bendamustine HydrochlorideFDA Link
12/2020 - 07/2007
5Bortezomib (Velcade)FDA Link
01/2015 - 06/2003
5Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
01/2014 - 11/2002
4Tretinoin (Retinoic Acid)FDA LinkGeneric
12/2021 - 08/2003
4Interferon-alpha (Interferon Alfa)IBA
09/2021 - 11/2004
4Core Binding Factors (Core-Binding Factor)IBA
01/2020 - 04/2005
4Etoposide (VP 16)FDA LinkGeneric
04/2018 - 04/2005
3CytokinesIBA
01/2020 - 09/2003
3RNA (Ribonucleic Acid)IBA
01/2019 - 08/2003
3IfosfamideFDA LinkGeneric
04/2018 - 01/2006
3Phosphotransferases (Kinase)IBA
12/2014 - 02/2006
3Proteasome InhibitorsIBA
06/2012 - 09/2008
3Cyclin D1IBA
12/2009 - 01/2009
3OligonucleotidesIBA
10/2009 - 08/2003
3CCAAT-Enhancer-Binding Protein-alphaIBA
02/2006 - 07/2002
2venetoclaxIBA
12/2022 - 12/2020
2NucleotidesIBA
10/2021 - 01/2016
2Daunorubicin (Cerubidine)FDA LinkGeneric
01/2020 - 12/2003
2Chlorambucil (Leukeran)FDA Link
01/2018 - 09/2006
2Complement System Proteins (Complement)IBA
11/2016 - 01/2005
2CreatinineIBA
08/2016 - 10/2012
2Cisplatin (Platino)FDA LinkGeneric
08/2016 - 09/2002
2fms-Like Tyrosine Kinase 3IBA
01/2016 - 05/2005
2purineIBA
01/2015 - 09/2004
2Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
11/2009 - 11/2006
2HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
06/2009 - 04/2003
2pegfilgrastim (Neulasta)FDA Link
04/2009 - 09/2003
2ProteomeIBA
12/2007 - 11/2006
2RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
12/2006 - 07/2003
2ibritumomab tiuxetan (Zevalin)FDA Link
08/2006 - 01/2005
2NucleophosminIBA
06/2006 - 12/2005
2Transcription Factors (Transcription Factor)IBA
08/2005 - 07/2003
2promyelocytic leukemia-retinoic acid receptor alpha fusion oncoproteinIBA
04/2005 - 01/2002
2CD40 Ligand (CD40L)IBA
09/2002 - 09/2002
1EpitopesIBA
09/2022
1T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
09/2022
1isocitric acid (isocitrate)IBA
01/2022
1Long Noncoding RNAIBA
01/2022
1Arsenic Trioxide (Trisenox)FDA Link
12/2021
1RNA Splicing FactorsIBA
10/2020

Therapy/Procedure

69Therapeutics
12/2022 - 06/2002
44Drug Therapy (Chemotherapy)
03/2022 - 01/2003
13Stem Cell Transplantation
09/2021 - 11/2004
6Chemoradiotherapy
08/2016 - 11/2003
5Immunotherapy
09/2022 - 07/2007
5Transplantation
01/2016 - 01/2004
4Salvage Therapy
01/2020 - 09/2006
4Induction Chemotherapy
01/2018 - 01/2009
4Palliative Care (Palliative Therapy)
01/2017 - 04/2005
3Homologous Transplantation
02/2014 - 07/2005
3Time-to-Treatment
12/2012 - 03/2005
2Neoadjuvant Therapy
04/2018 - 07/2002
2Critical Care (Surgical Intensive Care)
01/2017 - 01/2016
2Hematopoietic Stem Cell Transplantation
01/2016 - 01/2013
2Radioimmunotherapy
08/2006 - 07/2005